The error is:
This error (HTTP 404 Not Found) means that Internet Explorer was able to connect to the website, but the page you wanted was not found. It's possible that the webpage is temporarily unavailable. Alternatively, the website might have changed or removed the webpage.
For more information about HTTP errors, see Help.
The address bar reads:
http://localhost/mhnk
this is the site created in IIS by the Web PI that installed Kartris. Yes it is port 80.
I can install and run the site in IIS 8.0 Express, is that how you did it? I would prefer to install and run the site in the full IIS not the express. I would expect since you can install the site from the full IIS's Web PI it should work out of the box so I think I'm missing something or the installer is.